Endocrine Abstracts

We estimated androgen status at 111 female patients (pts) with HH before and after hormonal therapy (HT) by estadiol 2 mg+dydrogesterone 10 mg in sequence manner not <12 months. Median age of pts was 28 y.o., mean duration of HH 6.2 year, isolated HH n=56 group 1, HH as a part of hypopituitarism n=55 group 2, 45 healthy women of the same age were included in control group. Total T, SHBG and DHEA-S levels were measured, free T levels were calculated using stan...

Patients with Cushing’s disease were treated with proton beam surgery (pituitary irradiation) and the long-term results were studied. Hormone levels in 197 patients with the verified Cushing’s disease (161 woman and 36 men) were monitored after proton irradiation. Age of patients before irradiation is 17–54 years. Duration of supervision is 1–24 years.In peripheral blood, the concentration of pituitary hormones (ACTH, prolactin, LH, F...

Recently, the phenomenon of macroprolactinaemia has manifested itself into a great interest for physicians. This problem forces both physicians and patient to waste sizeable resources, and can lead to iatrogenic and unjustified emotional stress and further material losses. At the same time the problem of differential diagnostics of pseudoprolactinomas and true prolactinomas remains challenging. The purpose of the present study was to determine the clinic-analytical repercussio...